| ncRNA name | S1PR1 shRNA |
| ncRNA Category | shRNA |
| Disease name | optic nerve injury |
| Species | Mus musculus |
| Tissues/Cell_line | retinas, optic nerves |
| Methods | shRNA knockdown, immunostaining, Western blot, qRT‐PCR |
| Expression pattern | associated |
| Functional description | Silencing S1PR1 with an adeno-associated virus serotype 2 (AAV2) containing a shRNA specific to S1PR1 (AAV2.shRNA-S1PR1) exacerbated the loss of RGCs induced by optic nerve crush. |
| PubMed ID | 27309795 |
| Year | 2016 |
| Title | Sphingosine 1-phosphate receptor 1 is required for retinal ganglion cell survival after optic nerve trauma. |
| Drug-related ncRNA | NA |
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